HRT- Combipatch

Different Forms of HRT: Combipatch

(estradiol and norethindrone patch)

Introduced in late 1998, CombiPatch is notable because it is the first patch that delivers both estrogen and progesterone -- more specifically, estradiol and norethindrone acetetate (NETA). Like the estrogen-only matrix patches, the CombiPath is a thin, unobtrusive patch that delivers hormones through your skin. But because you get both estrogen and progestin from the patch, you don’t have to take any pills in addition to using the patch -- all you have to do is stick the patch on and change it twice a week. It’s that simple.

The clinical trials conducted before CombiPatch was approved found the most common side effects to be breast tenderness and breakthrough bleeding. But because the progestin in the patch is NTA, it probably will cause fewer side effects than other progestins. All in all, this looks like an excellent choice for a woman who prefers a patch to a pill -- and likes the idea of getting everything in one simple step.

Standard dosage: .05 mg estradiol; .014 mg NETA; .05 mg estradiol, .025 mg NETA

Pros: Very easy to use -- one patch gives you everything you need; supplies steady dosage of both estrogen and progestin

Cons: As with other patches, may cause allergic skin reactions